The Three Rs Principle
The NACLAR Guidelines on the Care and Use of Animals for Scientific Purposes was released in October 2004. The scope of the Guidelines covers all aspects of the care and use of animals for scientific purposes including their use in teaching, field trials, environmental studies, research, diagnosis, product testing, and the production of biological products. The aim of the NACLAR Guidelines is to promote humane and responsible care and use of animals for scientific purposes in Singapore.
In essence, the NACLAR Guidelines are based on the principles of the 3Rs- Replacement, Reduction and Refinement.
- Replacement of animals with alternative methods;
- Reduction of the number of animals used;
- Refinement of projects and techniques used to minimise impact on animals.
The Guidelines also outline the responsibilities of institutions, investigators and persons involved in the care and use of animals for scientific purposes. All research facilities which house and use animals for scientific purposes will have to operate in accordance with the Guidelines to qualify for licensing from AVA.
The Guidelines also describe the operational aspects pertaining to the Institutional Animal Care and Use Committee (IACUC). The IACUC is responsible for the oversight and evaluation of animal care and use programmes of an institution, and is responsible for ensuring that the care and use of animals for scientific purposes and all animal experimental procedures are in compliance with the Guidelines. Under the Guidelines, all institutions with research facilities are required to establish their own IACUC to assume this function.
The last section of the Guidelines outlines the training scope and requirements for users of animals and animal institution personnel. This includes the scope of the core curriculum and the relevant core competencies, such as special courses for animal procedures. The Guidelines require all users of animals for research to undergo appropriate training before carrying out any experiments involving animals. It will assist IACUCs in determining the scope and depth of education training programmes that will meet both institutional needs and the requirements of NACLAR.
For the NACLAR Guidelines, please see Guidelines on the Care and Use of Animals for Scientific Purposesopens in a new w.
National Advisory Committee for Laboratory Animal Research (NACLAR)
20 Biopolis Way
Tel: (65) 6826 6375
Fax: (65) 6478 9581